FBI Agent Sean Archer is consumed by grief for his deceased son and driven to capture his sworn enemy, Castor Troy. After a fierce battle, Archer finally corners Troy, but the criminal's bomb threatens to destroy Los Angeles. With only Troy's brother Pollux knowing the bomb's location, Archer undergoes a face transplant surgery to interrogate him. However, Castor Troy miraculously regains consciousness and seeks revenge against Archer, complicating both his mission and personal life.

Face/Off
A former FBI agent, consumed by grief, undergoes a groundbreaking facial transplant to infiltrate a terrorist organization, but the operation goes awry when the terrorist leader awakens prematurely, unleashing a devastating cycle of violence.