Scientists discover an alien plague that fills infected beings with overwhelming hatred, causing them to destroy everything in their path. To stop the Transformers, they plan to use Optimus Prime's lifeless body to lure them to a lab and infect them with the plague.

Transformers: The Return of Optimus Prime
A deadly alien plague, the Sun Spores, transforms its victims into mindless destroyers, prompting scientists to consider drastic measures to prevent human extinction.