Baron Frankenstein arrives in a new town to collaborate with Dr. Brandt, but finds him in a mental institution after losing his mind. He takes a room at a boarding house run by Anna, who is engaged to Dr. Karl, a doctor at the asylum where Brandt is being kept. Frankenstein blackmails Karl and Anna to assist him in his quest to learn a secret Brandt was about to share, and kidnaps Brandt to transplant his brain into another body.

Frankenstein Must Be Destroyed
A renowned scientist, Baron Frankenstein, collaborates with a young doctor and his betrothed to pioneer a revolutionary brain transplant procedure, abducting a mentally troubled individual, Dr. Brandt, as the test subject.