Irish couple Johnny and Sarah Sullivan, along with their two remaining children, move to the United States after the tragic loss of their young son Frankie. They face a challenging new life in a run-down tenement, surrounded by drug addicts and transvestites. Despite the difficulties, they strive to create a supportive family environment and eventually form connections with their eccentric neighbors, including an artist with AIDS. The memory of Frankie weighs heavily on the family, especially as Sarah becomes pregnant again.

In America
An Irish family in Hell's Kitchen struggles to come to terms with a devastating loss, seeking comfort in the midst of overwhelming sorrow.