In the New Mexico desert, a child's discovery sets off a desperate battle against giant, atomic-spawned ants. As the creatures ravage the local population, a team of scientists and law enforcement join forces to destroy the colony. But when two queen ants escape to Los Angeles, the team must race against time to rescue missing children and eradicate the growing threat.

Them!
A catastrophic nuclear experiment in New Mexico sets off a chain reaction, transforming a typical ant species into gargantuan creatures, threatening to wipe out humanity from the face of the earth.