Nathalia Dill's acting career began with stage performances in plays like "A Glória deNelson" and "Jogos na hora da Sesta" in 2005. The same year, she received an invitation to join the cast of the HBO series "Mandrake" and appeared in "Rosas Negras" in 2006.
In 2007, Deborah Rios played the villain in the 15th season of "Malhação" while Nathalia worked as an extra on the show and attended the film "Tropa de Elite", playing a college student. The following year, Nathalia appeared in the films "Feliz Natal e Apenas o Fim" and "Apenas o Fim".
In 2009, Nathalia participated in her first starring telenovela, "Paraíso", where she portrayed the character Maria Rita (Santinha). She also took part in the special year-end show, C D E Factory, the same year.
In 2010, Nathalia played her second consecutive leading role in "Escrito nas Estrelas", portraying Viviane/Victoria. The following year, she was part of the cast in "Cordel Encantado", playing the role of "vigilante" Doralice Peixoto.