Tom Craig, a Boston pharmacist, moves to Sacramento, where he clashes with the city's powerful boss, Britt Dawson, who demands protection money from the community. Dawson sets Craig up for poisoning medicine, but Craig's reputation is restored during a Gold Rush outbreak.

In Old California
In the midst of the California Gold Rush, a determined pharmacist named Tom Craig establishes a pharmacy in Sacramento, only to find himself at odds with the cunning and ruthless Britt Dawson, a notorious figure in the region.