A nuclear-powered bus embarks on a perilous journey from New York to Denver, beset by a series of catastrophes orchestrated by a clandestine group tied to the oil industry. After the original driver suffers an injury, a former driving prodigy, now struggling to make ends meet, takes the wheel of the eccentric bus, which features a swimming pool and bowling alley, and must navigate the treacherous route.

The Big Bus
A high-tech bus carrying nuclear energy embarks on a treacherous trip from New York City to Colorado, with a clandestine alliance between the oil industry and a malevolent group posing a significant threat to the transport and potentially triggering a devastating chain reaction.