The Great Indian Wars began in 1540 after Francisco Vazquez de Coronado's expedition to the Great Plains, sparking a 350-year struggle between the white man and American Indians. The conflicts, including the Battle of Tippicanoe, the Battle of Horseshoe Band, the Seminole Wars, and the Battle of Little Big Horn, ultimately led to the Battle of Wounded Knee, forever changing America's landscape.
The Great Indian Wars 1540-1890
In 1540, European settlers arrived, sparking a century-long conflict with Native American tribes, initiated by Coronado's expedition to the Great Plains.