Three adult sisters from a show business family navigate their personal and professional lives while dealing with their complicated relationships with each other and their family. Hannah, the successful and responsible sister, takes a break from her acting career to raise her children, but struggles to open up to others about her feelings. Holly, the insecure and flaky sister, is a struggling actress who turns to her sister Hannah for everything, including financial support. Lee, the youngest sister, is a free spirit who lives with an artist and is waiting for the right person to come along and help her find her place in the world. As the sisters navigate their relationships and careers, they must also confront their own insecurities and learn to communicate with each other in a more honest and open way.

Hannah and Her Sisters
A tangled web of family connections ensues when Hannah's husband becomes involved with her sister, while her ex-husband renews a bond with another sibling, two years after a dramatic Thanksgiving reunion.