A pig named Spider Pig is adopted by Homer after being saved from slaughter at Krusty Burger. Meanwhile, a lake is protected from pollution after a barge filled with garbage is sunk. However, Spider Pig's waste quickly fills a silo, and Homer inadvertently pollutes the lake by dumping the silo into it.

The Simpsons Movie
The Simpsons find themselves on the run as fugitives after Homer's careless actions contaminate the town's water supply, leading to a massive dome encasing Springfield and the EPA's pursuit of them.