Ana Luisa Peluffo embarked on her cinematic journey in 1953, marking the beginning of a remarkable career that would eventually earn her a revered status in Mexican film history. Notably, she became a trailblazer by appearing in nude scenes in mid-decade, a bold move that not only garnered attention but also paved the way for her to transition into a wide range of roles, including dramas and comedies. Although she returned to her roots in the 1970s, Peluffo's impressive filmography, boasting one of the longest and most extensive of any featured actress in Mexican cinema, is a testament to her enduring presence and versatility in the industry.
Throughout her illustrious career, Peluffo has received numerous accolades, including two Diosas de Plata awards. The first, awarded for Best Actress, was presented for her outstanding performance in the 1975 film "La venida del rey Olmos," while the second, received in 1996, honored her remarkable longevity and dedication to her craft.