Spencer is a native of Montgomery, Alabama, which she proudly claims is the proverbial buckle of the Bible belt. As the sixth of seven siblings, she developed a strong sense of family values and a deep appreciation for her roots. Her academic pursuits led her to earn a Bachelor of Science degree in Liberal Arts from Auburn University.
Despite her practical upbringing, Spencer harbored a secret passion for acting. She never imagined that her love for the performing arts would one day propel her to the big screen. However, in 1995, acclaimed director Joel Schumacher gave her a small but significant role opposite Sandra Bullock in the hit film A Time to Kill, marking the beginning of her journey in the film industry.
The following year, Spencer reunited with Bullock for the actress's directorial debut, Making Sandwiches, a short film that premiered at the 1997 Sundance Film Festival. This collaboration not only showcased Spencer's talent but also laid the groundwork for her future success.
Spencer made her stage debut in Los Angeles, originating the role of "LaSonia" (pronounced lasagna) in renowned writer/director Del Shore's, The Trials and Tribulations of a Trailer Trash Housewife, starring alongside veteran actors Beth Grant, Dale Dickey, and David Steen in 2003. The play received widespread critical acclaim and numerous awards, cementing Spencer's status as a talented and versatile actor.
Since then, Spencer has continued to thrive in both film and television, working alongside Hollywood's elite. In February 2009, she received recognition from The Envelope, a publication of the Los Angeles Times, for her poignant performance in the Will Smith drama Seven Pounds.