A child genius, Sheldon Cooper, uses his exceptional intellect to navigate life's challenges and overcome social impairments with the support of his family.
Aired: Jan 3, 2006Aired: Jan 4, 2006Aired: Jan 5, 2006Aired: Jan 6, 20065. Dominic Monaghan, Lil' Wayne
Aired: Jan 9, 20066. Quentin Tarantino, Tia Carrere, John Daly
Aired: Jan 10, 20067. David Boreanaz, Henry Phillips
Aired: Jan 11, 20068. Evangeline Lilly, Jonathan Rhys-Meyers, Giant Drag
Aired: Jan 13, 2006Aired: Jan 16, 200610. Michael Chiklis, Roselyn Sanchez, Bo Bice
Aired: Jan 17, 200611. Adewale Akinnuoye-Agbaje, Drew Lachey, Chamillionaire ft. Lil' Flip
Aired: Jan 18, 200612. Method Man, Motion City Soundtrack, Jerry Bruckheimer
Aired: Jan 20, 2006Aired: Jan 23, 200614. Regis Philbin, Jordana Brewster, She Wants Revenge
Aired: Jan 24, 200615. Jerry Rice, Mike Epps, Mike O'Connell
Aired: Jan 25, 200616. Martin Lawrence, Dem Franchize Boyz ft. Bow Wow, Jermaine Dupri
Aired: Jan 27, 200617. Kid Rock, David Alan Grier
Aired: Jan 31, 200618. David Spade, Rob Schneider, Jon Heder, Dwele
Aired: Feb 1, 200619. Michael Irvin, Jeff Daniels, The Four Tops, Buddy Guy
Aired: Feb 2, 200620. Jessica Alba, Anthony Anderson, The Four Tops
Aired: Feb 3, 2006Aired: Feb 5, 200622. Mischa Barton, Travis Barker & Shanna Moakler, James Blunt
Aired: Feb 6, 200623. Jorge Garcia, Dan Naturman, Nelly
Aired: Feb 7, 200624. Wilmer Valderrama, Dan Naturman, Golden Brooks, Dwight Yoakam
Aired: Feb 8, 200625. Nick Cannon, Kathy Griffin, Damian Marley
Aired: Feb 9, 200626. Steve Coogan, Travis Stork, Daddy Yankee
Aired: Feb 10, 200627. Freddie Prinze, Jr., John Daly, Jacks Mannequin
Aired: Feb 13, 2006Aired: Feb 14, 200629. Fred Savage, Harold Perrineau Jr., Yellowcard
Aired: Feb 15, 200630. Jack Osbourne, Carolyn Murphy, Dem Franchize Boyz
Aired: Feb 16, 200631. Shaun White, Steve Harvey, Hawthorne Heights
Aired: Feb 17, 200632. Kathie Lee Gifford, Yehya Mohamed, Augustana
Aired: Feb 21, 200633. Simon Cowell, Jennifer Esposito, Dilated Peoples
Aired: Feb 22, 200634. Cuba Gooding Jr., Mike Birbiglia
Aired: Feb 23, 200635. Paul Walker, Hannah Teter, Bow Wow, Travis Barker
Aired: Feb 24, 2006Aired: Feb 27, 200637. Stacy Keibler, Howie Mandel, Three Six Mafia
Aired: Feb 28, 200638. Jamie Oliver, Sasha Cohen, OK Go
Aired: Mar 1, 2006Aired: Mar 5, 2006Jimmy Kimmel hosts a special episode featuring a star-studded video with hims...
40. Zooey Deschanel, Dave Sheridan, Panic! At the Disco
Aired: Mar 6, 200641. Amanda Bynes, Chuck Lidell, Jamie Cullum
Aired: Mar 7, 200642. Michael Rapaport, Elisha Cuthbert, Matisyahu
Aired: Mar 8, 200643. John Lydon, Orlando Jones, Jim Gaffigan
Aired: Mar 10, 200644. Ice Cube, Elantu B. Veovode, Nine Black Alps
Aired: Mar 13, 200645. Adam Brody, John Cena, Juvenile featuring Galactic
Aired: Mar 14, 2006Adam Brody, John Cena, and Juvenile featuring Galactic appeared on Jimmy Kimm...
46. Randy Jackson, Janet Reno, Hard-Fi
Aired: Mar 15, 200647. James Caan, Justin Chambers, The Tossers
Aired: Mar 17, 200648. Hulk Hogan, Yunjin Kim, Harold & Darrell Allen
Aired: Mar 20, 200649. George Lopez, Duane "Dog" Chapman, the Sounds
Aired: Mar 21, 200650. Jamie-Lynn Sigler, Larry the Cable Guy, Gogol Bordello
Aired: Mar 22, 200651. Kiefer Sutherland, Rocco DeLuca
Aired: Mar 24, 200652. Seth Green, Chop from "King of Cars," Anthony Jeselnik, John Anderson
Aired: Apr 3, 200653. Anthony Anderson, Pete Rose
Aired: Apr 4, 200654. Carmen Electra, David Gest, People in Planes
Aired: Apr 5, 200655. Tori Spelling, C. Thomas Howell, T.I.
Aired: Apr 7, 200656. Rebecca Romijn, Judge Marilyn Milian, T-Pain
Aired: Apr 10, 200657. Chris Matthews, Craig Bierko
Aired: Apr 11, 200658. Wilmer Valderamma, Chris Elliott, The Wiggles
Aired: Apr 12, 200659. Charlie Sheen, Rube Goldberg Contest winners, K.T. Tunstall
Aired: Apr 14, 200660. Paula Abdul, Enrico Colantoni, Mighty Gonzalez
Aired: Apr 17, 200661. Cheryl Hines, Landon Donovan, Bril
Aired: Apr 18, 200662. Eva Longoria, Dick Cavett, Dresden Dolls
Aired: Apr 19, 200663. Regis Philbin, Barry Watson, Mike Birbiglia
Aired: Apr 21, 200664. Natasha Henstridge, Robert Wuhl, the cast of MTV's "Call to Greatness"
Aired: Apr 24, 2006Aired: Apr 25, 200666. Guy Pearce, Ludacris, Atmosphere
Aired: Apr 26, 200667. Susan Lucci, Adam Carolla, Rihanna
Aired: Apr 27, 200668. Joe Gannascoli, Kellie Pickler, Adam Carolla, Godsmack
Aired: Apr 28, 200669. Jenny McCarthy, Seth MacFarlane, The Cult
Aired: May 1, 200670. Sir Ian McKellen, Jared Leto, Franz Ferdinand
Aired: May 2, 200671. Chris O'Donnell, American Chopper Guys
Aired: May 3, 200672. Kathie Lee Gifford, Isaiah Washington, Art Brut
Aired: May 4, 200673. Famke Janssen, Jared Leto, 30 Seconds to Mars
Aired: May 5, 200674. Carl Reiner, Ashley Tisdale, Ivan Kane's Royal Jelly dancers, Martin Fry
Aired: May 8, 200675. Reggie Bush, Pat O'Brien, Lacuna Coil
Aired: May 9, 200676. Jamie Kennedy, Daryl Hannah, Jonathan Rice
Aired: May 10, 200677. Rev. Jesse Jackson, Jimmy Bennett, Nick Lachey
Aired: May 11, 200678. Dominic Monaghan, J.J. Abrams, Taking Back Sunday
Aired: May 12, 200679. Katherine Heigl, James Pickens Jr., Chandra Wilson, Ben Lee
Aired: May 15, 200680. Drew Carey, Malcolm David Kelley, Christina Milian
Aired: May 17, 200681. Teri Hatcher, Umphrey's McGee featuring Huey Lewis
Aired: May 18, 200682. Sarah Silverman, Artie Lange, Hoobastank
Aired: May 19, 200683. Sarah Silverman, James Cramer, Denny "Average Homeboy" Blaze
Aired: May 22, 200684. Julia Stiles, Jason Ritter, Atreyu
Aired: May 23, 200685. Jon Favreau, Mike Iaconelli, Elefant
Aired: May 24, 2006Aired: May 26, 2006Aired: Jun 6, 200688. Jessica Alba, Larry the Cable Guy, Him
Aired: Jun 7, 200689. Rosie Perez, Jared Hess, Elefant
Aired: Jun 8, 200690. John C. Reilly, Gary Gulman
Aired: Jun 9, 200691. Jaime Pressly, Xzibit, The Streets
Aired: Jun 13, 200692. Luke Perry, Jean Smart, Huey Lewis
Aired: Jun 14, 2006Aired: Jun 15, 2006Aired: Jun 16, 200695. Ozzy Osbourne, Anthony Bourdain
Aired: Jun 20, 200696. Bonnie Hunt, Phil Gordon, Buckcherry
Aired: Jun 21, 200697. Geena Davis, Louis C.K., Jeff Corwin
Aired: Jun 22, 2006Aired: Jun 23, 200699. Jason Alexander, Meagan Good, Jamie Kennedy
Aired: Jun 26, 2006100. Tommy Lee, 98-year-old high school student Josephine Belasco, Greg Fitzsimmons, the Fixx
Aired: Jun 27, 2006101. George Foreman, psychotherapist Richard Cohen, Blue October
Aired: Jun 28, 2006102. Kathy Griffin, Jason Gray-Stanford, the Brand New Heavies
Aired: Jun 30, 2006103. Ed Burns, NBA Finals MVP Dwayne Wade, Flyleaf
Aired: Jul 10, 2006104. Tracy Morgan, Shaun Alexander, Sonic Youth
Aired: Jul 11, 2006105. Lance Armstrong, Matt Dallas, Smoosh
Aired: Jul 12, 2006106. Brittany Murphy, Danica Patrick, Eagles of Death Metal
Aired: Jul 14, 2006107. Terrell Owens, Rainn Wilson, Rascal Flatts
Aired: Jul 17, 2006108. Shawn & Marlon Wayans, Fred Willard, Korn
Aired: Jul 18, 2006109. Robin Williams, Anna Faris, Rhymefest
Aired: Jul 19, 2006110. Allison Janney, Morgan Spurlock, Jurassic 5
Aired: Jul 21, 2006111. Rosario Dawson, Jesse Metcalf, the Flaming Lips
Aired: Jul 24, 2006112. Gene Simmons, Jeff Ross, the Elected
Aired: Jul 25, 2006113. Jon Cryer, the Dudesons, Los Lonely Boys
Aired: Jul 26, 2006114. Regis Philbin, Trevor Fehrman, Pharrell
Aired: Jul 28, 2006115. Flavor Flav, Leslie Bibb, Ben Harper
Aired: Jul 31, 2006Aired: Aug 1, 2006117. Cheryl Hines, Shaun White, Russell Peters
Aired: Aug 2, 2006118. Will Ferrell, Bobby Cannavale, Under the Influence of Giants
Aired: Aug 4, 2006119. Matt Dillon, Justin Long, Ziggy Marley
Aired: Aug 14, 2006120. Jonathan Winters, Kenan Thompson, Against Me!
Aired: Aug 15, 2006121. Paul Reubens, snake handler Jules Sylvester, Obie Trice, Leonid "the Magnificent" Filatov
Aired: Aug 16, 2006122. Samuel L. Jackson, Elisha Cuthbert, Cobra Starship
Aired: Aug 18, 2006
123. Heidi Klum, Dave Navarro, Panic Channel
Aired: Aug 21, 2006A child genius, Sheldon Cooper, uses his exceptional intellect to navigate li...
124. Hillary Duff, Ultimate Fighting Champion Chuck Lidell, Anti-Flag
Aired: Aug 22, 2006125. Tom Cavanaugh, Tommy Chong, Cartel
Aired: Aug 23, 2006126. Anthony Michael Hall, Joan & Melissa Rivers, the Red Jumpsuit Apparatus
Aired: Aug 25, 2006127. Kevin Nealon, Jay Chandrasekhar, Pat Green
Aired: Aug 29, 2006128. Tommy Lee, Wayne Brady, Starsailor
Aired: Aug 30, 2006129. Michael Rapaport, Jimmie Johnson, Jo Koy, Wayman Tisdale
Aired: Sep 1, 2006130. Lauren Holly, private investigator Vinny Parco, the Roots
Aired: Sep 5, 2006131. Ron Livingston, Toby Keith
Aired: Sep 6, 2006132. Anthony Michael Hall, James Carville, Robert Randolph and the Family Band
Aired: Sep 7, 2006133. Tyra Banks, Jason Statham, Papa Roach
Aired: Sep 8, 2006134. Orlando Bloom, Emily Deschanel, Lyfe Jennings
Aired: Sep 12, 2006135. Diane Lane, celebrity photographer Yehya Mohamed, Chingy
Aired: Sep 13, 2006136. Chris Elliott, Rachel Bilson, LeToya
Aired: Sep 14, 2006137. Sarah Silverman, Lionel Richie
Aired: Sep 15, 2006138. Zach Braff, Xzibit, Josh Radin
Aired: Sep 19, 2006139. Dwayne "The Rock" Johnson, Bam Margera, Lupe Fiasco
Aired: Sep 20, 2006140. Felicity Huffman, Jet Li, Human League
Aired: Sep 21, 2006141. Johnny Knoxville, Kim Raver, Patrizio
Aired: Sep 22, 2006Aired: Sep 26, 2006143. Jon Heder, Don, Mole and Perry, The Red Jumpsuit Apparatus
Aired: Sep 27, 2006144. Evangeline Lilly, Anthony Anderson, Ludacris
Aired: Sep 28, 2006145. Eva Longoria, Artie Lange
Aired: Sep 29, 2006146. Dax Shepard, Jordana Brewster, The Killers
Aired: Oct 3, 2006147. Dane Cook, Emilie de Ravin, The Killers
Aired: Oct 4, 2006148. Jessica Simpson, Carlos Mencia, The Killers
Aired: Oct 5, 2006149. Andy Dick, Diora Baird, Jet
Aired: Oct 6, 2006150. Jason Lee, America Ferrera, Gym Class Heroes
Aired: Oct 10, 2006151. Wanda Sykes, Sun Ming Ming, Ruben Studdard
Aired: Oct 11, 2006152. Robin Williams, Rod Stewart
Aired: Oct 12, 2006153. Justin Timberlake, Kate Walsh
Aired: Oct 13, 2006154. John Stamos, Bobcat Goldthwait, Ivan Kane's Royal Jelly
Aired: Oct 17, 2006Aired: Oct 18, 2006156. Ted Danson, Jennifer Tilly, Xzibit
Aired: Oct 19, 2006157. Terry Bradshaw, Matt Davis, Lloyd Banks
Aired: Oct 20, 2006158. Kathy Griffin, Shawnee Smith, Meat Loaf
Aired: Oct 31, 2006159. Sharon Osbourne, Josh Radnor, the Wreckers
Aired: Nov 1, 2006160. Roseanne Barr, Joseph Cross
Aired: Nov 2, 2006161. Val Kilmer, Bowling for Soup
Aired: Nov 3, 2006162. Lauren Graham, Ricardo Chavira, Anita Baker
Aired: Nov 6, 2006Aired: Nov 8, 2006164. Julia Louis-Dreyfus, Lady Sovereign
Aired: Nov 9, 2006165. Don Rickles, Nick and Aaron Carter, The Hold Steady
Aired: Nov 10, 2006166. Pamela Anderson, Geraldo Rivera, Brent Simon
Aired: Nov 13, 2006167. Tracy Morgan, Jerry Springer, Akon
Aired: Nov 14, 2006168. Brittany Murphy, Shia LaBeouf, John Legend
Aired: Nov 15, 2006169. Greg Kinnear, Marla Sokoloff, Sherrod Small
Aired: Nov 16, 2006170. Billy Crystal, Ricky Martin
Aired: Nov 17, 2006171. Teri Hatcher, Gary Brolsma, Rock Star Supernova
Aired: Nov 21, 2006Aired: Nov 22, 2006173. Wilmer Valderrama, Michael Irvin, Chris Daughtry
Aired: Nov 28, 2006174. Taye Diggs, Teri Garr, Todd Glass
Aired: Nov 29, 2006175. Rachel Weisz, Chi McBride, Jenny Lewis
Aired: Nov 30, 2006176. Elijah Wood, Tichina Arnold, Mute Math
Aired: Dec 1, 2006177. David Allen Grier, Tatum O'Neal, Lily Allen
Aired: Dec 5, 2006178. Thandie Newton, Peter Falk, Bow Wow with Chris Brown
Aired: Dec 6, 2006179. Tom Arnold, Jo Frost, Corinne Bailey Rae
Aired: Dec 7, 2006180. Ted Danson, Mary J. Blige
Aired: Dec 8, 2006181. Jessica Biel, Mario Batali, Fantasia
Aired: Dec 12, 2006182. Shawn and Marlon Wayans, Eric Dane, The Living End
Aired: Dec 13, 2006Aired: Dec 14, 2006184. Howard Stern, Forest Whitaker, Nas
Aired: Dec 15, 2006185. Matthew Fox, Lawrence Taylor, +44
Aired: Dec 19, 2006186. Adam Carolla, Giovanni Ribisi, OK Go
Aired: Dec 20, 2006187. Sylvester Stallone, Gnarls Barkley
Aired: Dec 21, 2006188. Matthew McConaughey, Yao Ming, Tracy McGrady, Hall & Oates
Aired: Dec 22, 2006189. George Lopez, Giuliana DePandi, My Chemical Romance
Aired: Jan 2, 2006
