Megan Mullally's talk show features the comedienne and actress sharing her wit, humor, and stories with her guests and audience in a hilarious and engaging format.
1. Will Ferrell, Jenny McCarthy
Aired: Sep 18, 20062. Eva Mendes, "So You Think You Can Dance", Granny Basketball
Aired: Sep 19, 20063. Lisa Kudrow, 10 year-old Opera Singer, Adam Rodriguez
Aired: Sep 20, 20064. Carol Burnett, Rainn Wilson, Hollerin' Championships
Aired: Sep 21, 20065. Felicity Huffman, 'Animal Guys' Paul Hahn and David Riherd, Enrique Murciano
Aired: Sep 22, 20066. Julia Louis-Dreyfus, Illusionist Criss Angel, Mario Lopez
Aired: Sep 25, 20067. Debra Messing, Fashion Makeover with Lucky Magazine, Omar Epps
Aired: Sep 26, 20068. George Lopez, Jennifer Finnigan, Vacuum Cleaning Genius, Tim Bagley At A Cher Convention
Aired: Sep 27, 2006Aired: Sep 28, 200610. Patricia Heaton, Duane Martin, Jesse McCartney
Aired: Sep 29, 200611. Jane Kaczmarek, Masi Oka, Champion Cloggers
Aired: Oct 2, 200612. Tom Bergeron, Eric Stromer, Elizabeth Perkins
Aired: Oct 3, 2006Aired: Oct 4, 200614. Connie Britton, Michael Clark Duncan
Aired: Oct 5, 200615. Jennifer Love Hewiitt, Jonny Lee Miller, J. Xavier
Aired: Oct 6, 200616. Virginia Madsen, Noah Gray-Cabey, Around The Office
Aired: Oct 9, 200617. Marcia Cross, Clinton Kelly, Isaiah Washington
Aired: Oct 10, 2006Aired: Oct 11, 200619. Wanda Sykes, Goran Visnjic, Ruben Studdard
Aired: Oct 12, 200620. Peter Gallagher, Nathan Burton, Tyler James Williams
Aired: Oct 13, 200621. Bradley Whitford, Shelley Morrison, Eric Mabius, Mario Vazquez, Phil Pfister
Aired: Oct 16, 200622. Cheyenne Kimball, Laura Linney, Ricardo Antonio Chavira
Aired: Oct 17, 200623. Merv Griffin, Kim Raver, Author Jennifer Egan
Aired: Oct 18, 200624. Rob Morrow, Rebecca Cole, Anne Heche, Joshua Bell
Aired: Oct 19, 200625. Josh Duhamel, Alison Lohman, Authors Mark Leyner and Billy Goldberg, Aly & AJ Michalka
Aired: Oct 20, 200626. Kristin Chenoweth, Jill Conner Browne, Nick & Aaron Carter, the Sweet Potato Queens
Aired: Oct 23, 200627. Jamie Lee Curtis, The Mystic Pixies, Amy Smart, Taylor Swift
Aired: Oct 24, 200628. Lauren Holly, Ruben Studdard, Daniel Dae Kim
Aired: Oct 25, 200629. Cloris Leachman, Jensen Ackles, Dog Halloween Costumes with Teri Austin, ecostylist Danny Seo
Aired: Oct 26, 200630. James Denton, Yahoo 9's Maria Sansone, Angela Kinsey, JoJo
Aired: Oct 27, 200631. Steven Weber, Audra McDonald
Aired: Oct 29, 200632. Neil Patrick Harris, Kevin Federline
Aired: Oct 30, 200633. Jamie Kennedy, Jeffrey Sebelia, Meat Loaf, Card Thrower Rick Smith
Aired: Oct 31, 200634. Clay Aiken, Tysonia Tschinga "Real Life" Dancing with the Stars
Aired: Nov 1, 200635. Sean Hayes, Eddie Cibrian, Dog Whisperer Cesar Millan, Author Mitch Albom
Aired: Nov 2, 200636. Barry Manilow, Parminder Nagra, Tim Bagley visits "America's Got Talent", Kid's Ballroom Dancing
Aired: Nov 5, 200637. Mark Harmon, Hip Hop Champions, Constance Zimmer, Melora Hardin
Aired: Nov 6, 200638. Kevin Nealon, Antonio Sabato Jr.
Aired: Nov 7, 200639. Bob Saget, sex educator Sue Johanson
Aired: Nov 8, 200640. Molly Sims, Andrea Bowen, The Ten Tenors, Celebrity trainer Michael Carson
Aired: Nov 9, 200641. Cheryl Hines, Tim Gunn, Thanksgiving Dog Adoption Fashion Show
Aired: Nov 12, 200642. David Hyde Pierce, Linda Cardellini, Taylor Ware
Aired: Nov 13, 200643. Patricia Arquette, Champion Pirouette Dancer, Daily Candy Trends
Aired: Nov 14, 200644. Dax Shepard, Tom Arnold, Kimberley Locke
Aired: Nov 15, 200645. Reba McEntire, Patrick Wilson, RBD
Aired: Nov 16, 200646. Tom Bergeron, Trista and Ryan, Benji Schwimmer, Rupert Boneham
Aired: Nov 19, 200647. Sharon Stone, Scott Foley, Rusty Schwimmer, Paz Vega, Danny Seo
Aired: Nov 20, 200648. Wayne Brady, Penguins Pete and Penny, Nestle Toll House Bake Sale Finalist
Aired: Nov 21, 200649. Camryn Manheim, Phil Pfister, James Lesure, Author Karen Rizzo
Aired: Nov 23, 200650. Neil Patrick Harris, Josh Radnor, Alyson Hannigan, Jason Segel and Cobie Smulders
Aired: Nov 26, 2006
51. David Boreanaz and Julianne Nicholson
Aired: Nov 27, 2006David Boreanaz, known for his iconic role in "Bones," teams up with Julianne ...
52. Matthew Broderick, Donald Faison, Brian Baumgartner, the Bucket Boys, Catherine Lloyd Burns
Aired: Nov 28, 200653. Tracy Morgan, Melissa Peterman, Jarod Miller, Eric Stromer
Aired: Nov 29, 200654. Carrie Fisher, Paul Rodriguez, Nadine Velazquez
Aired: Nov 30, 200655. Rosanna Arquette, Tom Green, Adrian Pasdar
Aired: Dec 3, 200656. Marla Sokoloff, Taylor Hicks, "Campus Ladies"
Aired: Dec 4, 2006Aired: Dec 5, 200658. Carson Kressley, Beau Bridges, Amy Sedaris
Aired: Dec 6, 200659. Wendie Malick, Janice Dickinson
Aired: Dec 7, 200660. John Stamos, Brenda Strong, Cris Judd, Tyrese
Aired: Dec 10, 200661. David James Elliott, Michael Ealy, Lisa Edelstein, magician Nathan Burton
Aired: Dec 11, 200662. Jeffrey Tambor, Tisha Campbell, designer Mark Montano, Hall & Oates
Aired: Dec 12, 200663. Shawn and Marlon Wayans, Taylor Hicks
Aired: Dec 13, 200664. Oded Fehr, Rob Morrow, Rhea Perlman, Sarah Rush
Aired: Dec 14, 200665. Howie Mandel, Jennie Garth, Ahmet Zappa, psychic medium Lisa Williams
Aired: Dec 17, 200666. Jane Seymour, David Conrad, Ken Davitian, Joshua Radin
Aired: Dec 18, 200667. Alfre Woodard, Milo Ventimiglia, Fantasia Barrino
Aired: Dec 19, 200668. Billy Ray Cyrus, Richard Simmons, authors of "Party Confidential"
Aired: Dec 20, 200669. Hall & Oates, Brian McKnight, Clay Aiken, José Feliciano, Kimberley Locke, Celtic Woman
Aired: Dec 21, 200670. Emily Procter, Tichina Arnold, Goo Goo Dolls
Aired: Jan 7, 200771. Natalie Cole, Craig Bierko, Dave Annable, Blaine Zuckerman
Aired: Jan 8, 2007Guest Starring
