Dedee Pfeiffer, a talented actress, grew up in Midway City, California, as the daughter of a heating and air conditioning contractor and a homemaker. She was fortunate to have had the opportunity to study with some of Hollywood's most renowned acting coaches, including Peggy Feury, Roy London, and Ivana Chubbuck.
Pfeiffer's early career in the entertainment industry was marked by her landing a role in John Landis' film Into the Night and her first television role in the series Simon & Simon. She went on to star in the horror cult classic comedy Vamp, alongside the iconic actress and model, Grace Jones. Her impressive filmography also includes appearances in Falling Down and other notable television shows.
One of Pfeiffer's most notable roles was as Cybil Shepherd's daughter, Rachel, in the popular television series Cybil. The show earned nearly three dozen awards and nominations, including three Primetime Emmy awards and the Golden Globe Award for best television series - musical or comedy. Pfeiffer and the rest of the cast were also nominated for a Screen Actors Guild Award for outstanding performance by an ensemble in a comedy series.
In addition to her work on Cybil, Pfeiffer has also starred in the series For Your Love and guest starred in several iconic television shows, including Seinfeld, Friends, two CSI series, and ER. She has also appeared in numerous short films, including The Tub and Laredo, for which she won awards and nominations as an actor and producer.
In a bold move, Pfeiffer graced the cover of Playboy magazine's February 2002 issue, breaking with convention by posing nude with a BIPOC male model and showcasing her tattoo art. This appearance was significant, as it was a departure from the typical Playboy magazine fare and a testament to Pfeiffer's confidence and willingness to challenge the status quo.
After a 10-year hiatus from Hollywood, Pfeiffer returned to acting as a series regular on the ABC drama Big Sky, playing the role of Denise Brisbane.