Matthew's journey began as a pre-law student at Widener University, later shifting his focus to Criminal Justice at West Chester University. This marked the starting point of his illustrious career, which saw him make appearances on renowned television shows such as The Howard Stern Show in 1990 and The Oprah Winfrey Show in 1986. His talents also landed him roles in music videos for iconic bands like Iron Maiden, Marilyn Manson, and Blondie.
Matthew's cult following grew significantly due to his memorable performances in films like "Tiny" in Rob Zombie's House of 1000 Corpses in 2003 and Karl the giant in Tim Burton's Big Fish in the same year. Tragically, Matthew's life was cut short on August 9, 2005, due to natural causes. In his honor, a biopic about André René Roussimoff was in production at the time of his passing.