Vincent De Paul was born in Baltimore, Maryland, to a family with a rich history. His father, an amortuary scientist, owned funeral homes in Maryland, while his mother, a socialite, dedicated her time to charitable causes, including chairing committees for the March of Dimes, Children with Birth Defects, and Relief to Earthquake victims in Naples.
De Paul's early life was marked by his love for the arts, and he began his acting career with his first role as Beowolf in one of the oldest Scandinavian epics. This marked the beginning of his journey in the entertainment industry, which would span over 15 years.
After graduating from Johns Hopkins University in Baltimore, Maryland, with a degree in Epidemiology, Biomedical Ethics, and Bio statistics, De Paul moved to Miami Beach to work at Mt. Sinai Medical Center. It was during this time that he was discovered and began doing fashion shows for the late Gianni Versace.
Represented by Wilhelmina Creative, De Paul has worked internationally and has appeared in numerous magazines, including GQ, Vogue (Spain),Cosmopolitan (Greece, Spain, Poland, Russia),and Men's Health (Peru, Ecuador, USA edition in Spanish, Mexico, and Colombia).
He has also been featured in several campaigns worldwide, including L'Oreal (France) with Stephanie Seymour, El Corte Inglese (Spain) with Ricky Martin, Christian Dior (Latin America),Oscar De la Renta (Mexico),and FUJI (Mexico) Avon Campaign USA, Guy La Roche Campaign (USA and Canada).
De Paul's film career spans over a decade, with his first feature film being Hairspray, in which he played one of the original Corny Collins Dancers, directed by John Waters. He has also appeared in Riding in Cars with Boys with Drew Barrymore, as a Line Backer, directed by Penny Marshall.
His TV career includes appearances on West Wing, Frasier, Charmed, Sex in the City, HBO's Six Feet Under, and most recently, NBC's Medical Investigation. He has re-occurred for the last four years on As the World Turns as Charlie the Bartender at the Metro.
De Paul is also involved in several charitable causes, including serving on the Audrey Hepburn Red Rose Award committee with Sean Hepburn Ferrar. He volunteers his time at the House of Camillus for battered women.