In the midst of the 1970s, a trio of notorious crime bosses finds themselves pursued by both Italian and American law enforcement agencies.

The Rio Connection took place in the mid-1970s, as Italian and American authorities hunted down three notorious organized crime figures. Fearing capture, they escaped to Brazil, assuming new identities and starting a new venture.
In the midst of the 1970s, a trio of notorious crime bosses finds themselves pursued by both Italian and American law enforcement agencies.