The gang returns to East Great Falls, Michigan for their high school reunion, revisiting their lives over a decade later. They'll explore how Michelle, Jim, Heather, Oz, Kevin, Vicky, Finch, Stifler, and Stifler's mom have grown, after initially seeking to lose their virginity in 1999. Meanwhile, a new student, Kara, is now a high school senior on a quest to find the perfect partner to lose her virginity to.

American Reunion
The old friends reunite in their hometown of East Great Falls, Michigan, for a nostalgic high school reunion, reliving cherished memories and rekindling strong bonds.